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Online Journal of Bioinformatics ©
Volume 16 (1): 1-7, 2015.
Systems biology prediction for evolutionary process of coloured vision in mammals.
1Shivani Sharma, 2Prashant Saxena*
1Department of Life science, Institute of applied medicine and research, Duhai, Ghaziabad, Uttar Pradesh. 2Department of Bioinformatics, Sathyabama University, Chennai, Tamilnadu, India.
Sharma S, Saxena P., Systems biology prediction of evolutionary process for coloured vision in mammals, Onl J Bioinform, 16 (1): 1-7, 2015. Since Darwin, genetic change has been considered to be a direct indicator of variation in phenotype. Recently it has been proposed that epigenetic developmental processes affect phenotype shifting focus from a linear genotype-phenotype map to a non-linear G-P one. LWS opsin gene has a role in trichromatic vision in human beings and other mammals. LWS opsin gene is particularly sensitive to the green-yellow color range differentiating between vivid colors more clearly. We describe evolution of colour vision in mammals through the LWS long-wave sensitive gene mutations which lead to the different phenotypes. The opsin genes LWS, MWS and SWS contribute to a variable colour vision spectrum and we show that genotypic variation alone is not responsible for resulting genotypes in vision.
KEYWORDS: Evolution, Opsin gene, genotype, phenotype, color vision.