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Online Journal of Bioinformatics ©
Volume 7 (2): 85-89, 2006.
Dowlathabad MR1, Venkata RD2, Rallapalli R2
Biotechnology, Bioinformatics Laboratory and 2Department of
Dowlathabad MR, Venkata RD, Rallapalli R., In silico Homology modeling and Structure assessment of Holo (Acyl Carrier Protein) synthetase from Treponema pallidum, Onl J Bioinform., 10 (2) :85 - 89, 2006. Computational data provides new opportunities for finding optimal targets among previously unexplored cellular functions based on an understanding of their related biological processes in bacterial pathogens and their hosts. The experimental structure for Holo Acyl Carrier Protein synthetase of Treponema pallidum is still unknown for the reason that Treponema pallidum could not be grown in vitro conditions. A computational 3D model and structure assessment for ACP synthetase of Treponema pallidum is described with the aim of designing appropriate inhibitor(s) against acp synthetase of Treponema pallidum.
Key words: Troponema pallidum, Homology modeling, Holo (Acyl carrier protein) Synthetase