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OJBTM

Online Journal of Bioinformatics ©

Volume 17(3):159-167, 2016..


Homology modeling and molecular dynamic ABC transporter1 anti-bacterial in Antheraea mylitta

 

Krishna Madipelli, P Nagaraja Rao.

 

Department of Zoology, Osmania University, Hyderabad

 

ABSTRACT

 

Madipelli K, Rao PN., Homology modeling and molecular dynamic ABC transporter1 anti-bacterial in Antheraea mylitta Onl J Bioinform., 17(3):159-167, 2016... . Homology modeling has significant potential for high throughput In silico screening. We describe a method for discovery of 3D structures of anti-bacterial expressed proteins. A 3D model of ABC Transporter1 from Antheraea mylitta was generated using 1OXS as template and Modeller7v7 and optimized by Verify 3D and Procheck.  Flexible docking was performed with Sortase A using GOLD3.0.1 software. Results suggested that ARG 157, THR115, LEU242 in Sortase A are amino acids involved in docking and bonding.

 

Key words: Antheraea mylitta, Homology Modeling, ABC Transporter1, Docking.


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