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OJBTM

Online Journal of Bioinformatics 

Volume 12(1):46-56, 2011.


In silico epitope rabies virus vaccine.

 

Tomar N Ra *, Marla S S a, Chandra Rb, Kumar Rc and Kumar Aa

 

aDepartment of Molecular Biology and Genetic Engineering, G.B.Pant university of Agriculture and Technology, Pantanagar-263145,bDepartment of Veterinary Microbiology, G. B. Pant university of Agriculture and Technology, Pantanagar-263145,cAnimal Biotechnology section, Central Sheep and Wool Research Institute, Avikanagar-304501, India

 

ABSTRACT

 

Tomar NR, Marla SS, Chandra R, Kumar R, Kumar A., In silico epitope rabies virus vaccine, Online J Bioinform.atics, 12(1):46-56, 2011. An epitope from position 228-236 (T-228) was identified as a novel T cell epitope revealing good MHC class I binding, processing and conservation in known rabies viruses. The findings suggest that it may be possible to generate a synthetic peptide vaccine against rabies but further research on G protein is required, including a search for additional linear epitopes.

 

Key words: Epitope vaccine, T cell epitopes, in-silico, rabies.

 


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