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OJBTM
Online Journal of
Bioinformatics ©
Volume 15
(1): 49-53, 2014.
Proteome database for Mycobacterium tuberculosis strains H37Rv
versus H37Ra
Jena L1,2, Kumar S1*
1Bioinformatics Centre & Biochemistry,
Mahatma Gandhi Institute of Medical Sciences,
Sevagram, Maharashtra, 2Department
of Bioinformatics, Shri JJT University, Jhunjhunu, Rajasthan, India
Jena
L, Kumar S., Proteome database for Mycobacterium tuberculosis strains H37Rv
versus H37Ra, Onl J Bioinform.,
15 (1): 49-53, 2014. An online
proteome sequence database for Mycobacterium
tuberculosis (MTB) strain H37Rv versus H37Ra is
described. The database hosts 8031 protein sequences retrieved from whole
proteome comparison of MTB strains H37Rv against H37Ra.
Analysis identified 3759 identical proteins between the 2 strains, 244 proteins
of H37Rv were non-identical to H37Ra with multiple copies
in both strains. 172 proteins were identified with mutations
(Insertions/Deletions/Substitutions) in H37Ra and 53 in H37Rv.
85 proteins in H37Ra were distinct.
Keywords: Proteome comparison, tuberculosis, virulent,
database.
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