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 Online Journal of Bioinformatics


Volume 8 (1): 41-44, 2007.

Database and interactome map of genes involved in oral cancer


Gadewal NS1, Zingde SM2



1Bioinformatics centre (BTIS Sub-DIC), Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, India




Gadewal NS, Zingde SM., Database and interactome map of genes involved in oral cancer, Onl J Bioinform, 8 (1) 41-44, 2007.  In the post genomic era, efforts to understand oral cancer are aimed at obtaining genomic and proteomic profiles for cancer management. The database in this report provides information and external links for 242 genes involved in oral cancer, interactions between them, their role in the biology of oral cancer, along with clinical relevance. Each gene gives detailed information on aliases, function, chromosomal location, mutations and SNPs, mRNA expression, protein information, pathways involved and interacting proteins, expression of genes in different tissues, and clinical correlates. For querying the database a search engine retrieves the genes by symbol, name, chromosomal location, gains and losses of chromosomal regions and molecular weight. Interactome maps have been generated for the genes that are categorized into important biological processes and molecular functions based on Gene-Ontology.


KEYWORDS: Oral cancer, Database, Interactome map