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OJBTM

Online Journal of Bioinformatics©

Volume 1: 60-73, 2002.


BAO, A biological and chemical ontology for information integration.

 

Zina Ben Miled l* Yue W. Webster1 Nianhua Li2 Omran Bukhres2 Arun K. Nayar3 Jesse Martin3 Robert Oppelt3

 

1 Electrical Engineering Department, Purdue School of Eng. &: Tech. 2 Computer &: Information Science, Purdue School of Science 3 Lilly Corporate Center, Eli Lilly and Company.

 

ABSTRACT

 

BAO, A Biological and Chemical Ontology For Information Integration Miled ZB,  Webster YW Nianhua L, Bukhres O,  Nayar AK, Martin J, Oppelt R, Online J Bioinformatics, 1:60-73, 2002. BAO (BACIIS Ontology) is a domain ontology for BACIS (Biological And Chemical Information Integration System) - The main goals of BAO are: 1) to guide users in creating efficient queries, 2) to facilitate resolution of the variabilities among various data formats and data sources, and 3) to facilitate the integration of biological and chemical data web databases. In this paper, a three dimensional biochemical ontology, BAO is proposed following a well defined set of design and evaluation criteria. Its structure is more expressive, flexible and extendible than the traditional structures. The ontology is validated through its use to express comprehensive biological and chemical concepts. Furthermore, the advantages of the proposed design are addressed through a detailed comparison with the traditional approach. The ontology described in this paper is implemented using Powerloom. However, the same architecture can be implemented using other languages.

 

KEYWORDS: Ontology, Biology, Chemistry, integration, databases, interoperability


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