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OJBTM
Online Journal of Bioinformatics ©
Volume
11 (2): 282-292, 2010.
Building a topological inference with qualitative criteria to predict
the structural family of a protein sequence.
Omar Gaci
Le Havre University, Le Havre – France
ABSTRACT
Gaci O, Building a topological inference with
qualitative criteria to predict the structural family of a protein sequence, Onl J Bioinform, 11 (2): 282-292, 2010. The similarity between structural and topological properties were
used to predict the structural family of a protein sequence. The method
identified properties of the candidate families using sample proteins.
Properties of the target sequence were compared to the corresponding properties
of the families. Reliability was measured by comparing results to existing
structural classifications. The method uses graphed proteins, where the
vertices are amino acids, and the edges are interactions between them.
Key words: interaction
network, protein structure, structural classification
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