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OJBTM

 Online Journal of Bioinformatics  

Volume 1 (19):41-46, 2018.


In silico prediction of antigenic epitope of coat protein from soybean dwarf virus.

 

Gomase VS, Chikhale NJ

 

Govt. College of Pharmacy and Dept. of Biotechnology, Amravati University, Amravati. India

 

ABSTRACT

 

Gomase VS, Chikhale NJ., In silico prediction of antigenic epitope of coat protein from soybean dwarf virus, Onl J Bioinform., 1 (19):41-46, 2018. Soybean dwarf virus (SbDV) cell infection produces structural and nonstructural proteins in plants. A coat protein is the major protein of the virion involved in viral attachment, membrane fusion and host entry. Antigenic epitopes on this protein protect against virus infection and virus-neutralizing antibodies may be sufficient to impart immunity. The findings of this report suggest that epitopes RAPRVQLMAVPTVTS; SDGILKAYHEYKITSILLQFIT, 20-34; 93-114 of coat protein could be sufficient to induce an immune response. Peptides from sbDV protein that produce virus-neutralizing epitope(s) may therefore induce sbDV neutralizing antibodies.

 

KEY-WORDS- Soybean dwarf virus, coat Protein, antigenic epitope, immune response.


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