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 Online Journal of Bioinformatics ©

Volume 12(2):207-216, 2011

Comparative modeling studies of a hypothetical protein YHR105W from S.Cerevisae genome.

1N Rathankar, 2HG Nagendra*

1 Asst. Professor, School of Bioengineering, Department of Bioinformatics, SRM University, Kattankulathur campus, hennai and 2 Prof. and HOD, Dept. of Biotechnology, Sir M. Visvesvaraya Institute of Technology, Krishnadevarayanagar, unasamaranahalli, Bangalore, India.




Rathankar N, Nagendra HG., Comparative modeling studies of a hypothetical protein YHR105W from S. Cerevisiae genome, Onl J Bioinform, 12(2):207-216, 2011.The first Eukaryotic genome to be sequenced in 1966 was the common Bakerís Yeast, S.Cerevisae. It is used as a model organism, as it shares similarity with a vast number of genes, proteins andgenetic pathways in humans. A suitable sequence was selected for comparative modeling studies. Results revealed that, though the sequence similarity with the targets from PDB were lower than 25%, the structural homology between the template and the model hypothetical protein YHR105W was found to be high, suggesting similar functional roles.







Key Words: Modeled protein, S Cerevisae genome.