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Online Journal of Bioinformatics©
Established 1995
ISSN 1443-2250
Volume 20(1):1-8,
2019.
Insights into the mechanism of coccidiosis from
Isospora Suis
Eleni Picasi1, Panagiota Kaisaridi1, Kalliopi Io Diakou1, Konstantinos Kaliafentakis1,
Louis Papageorgiou1, Vasileios Megalooikonomou2, Dimitrios Vlachakis1,2,3,4†
1Genetics and
Computational Biology Group, Laboratory of Genetics, Department of
Biotechnology, Agricultural University of Athens, 75 Iera
Odos, 11855, 2 Computer Engineering and Informatics Department,
School of Engineering, University of Patras, 26500 Patras, 3Division of Endocrinology and Metabolism,
Clinical Research Center, Biomedical Research
Foundation of the Academy of Athens, Athens, Greece; 4Faculty of
Natural & Mathematical Sciences, King's College London, London, U.K.;† Correspondence should be addressed to Dimitrios Vlachakis
(dimvl@aua.gr)
ABSTRACT
Picasi E, Kaisaridi P, Diakou K, Kaliafentakis K, Papageorgiou L, Megalooikonomou V, Vlachakis D., Insights
into the mechanism of coccidiosis from Isospora Suis, Onl J Bioinform.,
20(1):1-8,
2019. Protozoa is a Greek term of protos=first
and zoon=animal. The term protozoon refers to ancient, unicellular,
heterotrophic, eukaryotic microorganisms, which are commonly parasitic animals
or plants. Many of them have kinetic abilities, thanks to their various
morphological characteristics, something that enriches them with animal
behavior features. Protozoa are parasites which reside mainly in the interior
of the hosts and not on their surface. These microorganisms parasitize on
plants or animals. Their dimension ranges from 10 to 52 micrometers. Coccidia is a subcategory of apicomplexan
protozoan, the largest group of parasitic protists.
Their host is animal cells, where they live and reproduce. Coccidial
parasites principally cause enteric infections to animals, known as
coccidiosis. This parasite usually affects young animals, which are housed or
piled in small areas, because of the sensitivity of their immune system. Under
certain circumstances, animals may develop symptoms of clinical coccidiosis.
Even though the most coccidial infections are
subclinical, that renders diagnosis difficult and as a consequence, encumbers
treatment. Coccidiosis is a parasitic disease caused by coccidian protozoa. Primary
symptoms are diarrhea, pain, loss of appetite and weight and general intestinal
problems. Its spread is rapid and it can be transmitted by contact with another
infected organism. Coccidiosis infects poultry, piglets and rabbits but can
infect almost every animal. As a result, coccidial
infections can cause a plethora of problems in the farming sector, state
economy, stock raising
which have an after effect on the human species. We describe the mechanism
of coccidiosis
from Isospora Suis.