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Online Journal of Bioinformatics©
Volume 20(1):1-8, 2019.
Insights into the mechanism of coccidiosis from Isospora Suis
Eleni Picasi1, Panagiota Kaisaridi1, Kalliopi Io Diakou1, Konstantinos Kaliafentakis1,
Louis Papageorgiou1, Vasileios Megalooikonomou2, Dimitrios Vlachakis1,2,3,4†
1Genetics and Computational Biology Group, Laboratory of Genetics, Department of Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855, 2 Computer Engineering and Informatics Department, School of Engineering, University of Patras, 26500 Patras, 3Division of Endocrinology and Metabolism, Clinical Research Center, Biomedical Research Foundation of the Academy of Athens, Athens, Greece; 4Faculty of Natural & Mathematical Sciences, King's College London, London, U.K.;† Correspondence should be addressed to Dimitrios Vlachakis (firstname.lastname@example.org)
Picasi E, Kaisaridi P, Diakou K, Kaliafentakis K, Papageorgiou L, Megalooikonomou V, Vlachakis D., Insights into the mechanism of coccidiosis from Isospora Suis, Onl J Bioinform., 20(1):1-8, 2019. Protozoa is a Greek term of protos=first and zoon=animal. The term protozoon refers to ancient, unicellular, heterotrophic, eukaryotic microorganisms, which are commonly parasitic animals or plants. Many of them have kinetic abilities, thanks to their various morphological characteristics, something that enriches them with animal behavior features. Protozoa are parasites which reside mainly in the interior of the hosts and not on their surface. These microorganisms parasitize on plants or animals. Their dimension ranges from 10 to 52 micrometers. Coccidia is a subcategory of apicomplexan protozoan, the largest group of parasitic protists. Their host is animal cells, where they live and reproduce. Coccidial parasites principally cause enteric infections to animals, known as coccidiosis. This parasite usually affects young animals, which are housed or piled in small areas, because of the sensitivity of their immune system. Under certain circumstances, animals may develop symptoms of clinical coccidiosis. Even though the most coccidial infections are subclinical, that renders diagnosis difficult and as a consequence, encumbers treatment. Coccidiosis is a parasitic disease caused by coccidian protozoa. Primary symptoms are diarrhea, pain, loss of appetite and weight and general intestinal problems. Its spread is rapid and it can be transmitted by contact with another infected organism. Coccidiosis infects poultry, piglets and rabbits but can infect almost every animal. As a result, coccidial infections can cause a plethora of problems in the farming sector, state economy, stock raising which have an after effect on the human species. We describe the mechanism of coccidiosis from Isospora Suis.