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OJBTM
Online Journal of
Bioinformatics ©
Volume 15 (2): 157-167, 2014
Finite
element model of calcium distribution in oocytes for one dimensional unsteady
state case.
Parvaiz Ahmad Naik* and Kamal Raj Pardasani.
Department of Mathematics, Maulana Azad
National Institute of Technology, Bhopal-462051, India.
ABSTRACT
Ahmad Naik P,
Pardasani KR., Finite element model of calcium
distribution in oocytes for one
dimensional unsteady state case, Onl J Bioinform., 15 (2): 157-167, 2014. Ca2+ is the second messenger
responsible for Oocyte maturation. The mechanisms involved in calcium dynamics
of oocyte maturation are poorly understood. In this paper an attempt has been
made to develop a model to estimate intracellular calcium concentration in
circular shaped oocyte. Essential parameters such as buffers, influx and
diffusion coefficient are incorporated in the model. Appropriate initial and
boundary conditions are framed. The finite element method has been employed to
solve the initial boundary value problem. The effect of buffers, influx and
diffusion coefficient on calcium concentration in oocyte has been resolved with
numerical results.
Keywords: Finite Element
Method, MATLAB, Buffers, Diffusion Coefficient, Reaction Diffusion Equations.
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