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OJBTM

 Online Journal of Bioinformatics  

  Volume 15 (2): 157-167, 2014


Finite element model of calcium distribution in oocytes for one dimensional unsteady state case.

 

Parvaiz Ahmad Naik* and Kamal Raj Pardasani.

 

Department of Mathematics, Maulana Azad National Institute of Technology, Bhopal-462051, India.

 

ABSTRACT

 

Ahmad Naik P, Pardasani KR., Finite element model of calcium distribution in oocytes for one dimensional unsteady state case, Onl J Bioinform., 15 (2): 157-167, 2014. Ca2+ is the second messenger responsible for Oocyte maturation. The mechanisms involved in calcium dynamics of oocyte maturation are poorly understood. In this paper an attempt has been made to develop a model to estimate intracellular calcium concentration in circular shaped oocyte. Essential parameters such as buffers, influx and diffusion coefficient are incorporated in the model. Appropriate initial and boundary conditions are framed. The finite element method has been employed to solve the initial boundary value problem. The effect of buffers, influx and diffusion coefficient on calcium concentration in oocyte has been resolved with numerical results.

 

Keywords: Finite Element Method, MATLAB, Buffers, Diffusion Coefficient, Reaction Diffusion Equations.


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