1996-2020. All Rights Reserved. Online Journal of Bioinformatics. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJIM publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


OJBtm

Online Journal of Bioinformatics

Established 1995

ISSN  1443-2250

 

Volume 20(2):62-75, 2019.


BTDB - Database on Structural and Functional Information of Biotoxins.

 

Gowriishankar R and Sundara Baalaji N*

 

Structural Biology lab, Department of Bioinformatics, School of life sciences, Bharathiar University, Coimbatore 641 046

 

ABSTRACT

 

Gowriishankar R, Baalaji SN., BTDB - Database on Structural and Functional Information of Biotoxins, Onl J Bioinform., 20(2):62-75, 2019. A biotoxic protein database could enable identification of membrane proteins, ion channels on the surface of cancer cells. We describe primary sequence databases for biotoxins from snake, spider and scorpion. We intended to study the 3D structures of the toxin proteins by homology modeling and validation of the structures through computational methods that will ease wet lab works. Structural features of the models and the putative functions are also predicted. For the easy access of the theoretically modeled proteins and other related data, database named BTDB was created which is user friendly and the information collected from this database will have the implications on further insilico analysis on cancer studies, designing drugs, studies on membrane proteins and identification of ion channels.

 

This database can be accessed at the URL: http://b-u.ac.in/btdb/

Keywords: Biotoxin, Polypeptide, Homology modeling, RMSD, Minimized energy, Database, HTML, MySQL