©2021-2032 All Rights Reserved. Online Journal of Bioinformatics. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to email@example.com publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. Linking: To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.
Online Journal of Bioinformatics©
Volume 23 (2):146-161, 2022.
In silico anoxia tolerance gene sequence residues.
TK Sahu MSc1, AR Rao PhD1, Alka BG MSc1, BK Behera PhD2,T Mohapatra PhD3.
1Indian Agricultural Statistics Research Institute, New Delhi, 2Central Inland Fishery Research Institute, Barrackpore, Kolkata, 3National Research Centre on Plant Biotechnology, New Delhi, India
Sahu TK, Rao AR, Alka BG, Behera BK, Mohapatra T., In silico anoxia tolerance gene sequence residues, Onl J Bioinfo., 23 (2):146-161, 2022. Vitellogenin (VTG) anoxia tolerant gene exists in fish and oviparous species whereas submergence 1 gene is found in plants such as rice. Due to function, both genes probably have a common evolution. We identify conserved and key residues for anoxia tolerance gene residues across species. Key residues of vitellogenin protein domain gene for Danio rerio were extracted for similarity search in mammals, amphibians, birds and insects. A similar search was done for submergence 1 gene with the plant Oryza spp. Both genes were subjected to multiple sequence alignment. Structure conservation of residues was determined by in silico proteomic analysis. Results suggest that arginine was conserved at a defined position in final alignment identified as key residue responsible for reduced oxygen tolerance across species. By evolution, proteins for submergence tolerance in aquatic plants are very close to proteins for anoxia tolerance in fishes.
Keywords: Anoxia, Zebrafish, Vitellogenin, Apolipophorin, Apolipoprotein, Submergence, Oryza sativa, Oryza rufipogon, Oryza nivara, abiotic stress.